Omics
Reproductive Omics
An emerging focus of my work is the integration of omics (e.g. metabolomic and epigenetic) technologies into studies of human reproduction to elucidate biologically relevant pathways associated with environmental exposures and reproductive health outcomes.
Key References:
Tang Z, Gaskins AJ, Hood RB, Ford JB, Hauser R, Smith AK, Everson TM. Former smoking associated with epigenetic modifications in human granulosa cells among women undergoing assisted reproduction. Sci Rep. 2024 Feb 29;14(1):5009. doi: 10.1038/s41598-024-54957-2. PMID: 38424222; PMCID: PMC10904848.
LaPointe S, Mehta A, Gaskins AJ. Diet and recreational drug use in relation to male reproductive health. Fertil Steril. 2023 Dec;120(6):1089-1097. doi: 10.1016/j.fertnstert.2023.10.013. Epub 2023 Oct 12. PMID: 37838140.
Hwang S, Hood RB, Hauser R, Schwartz J, Laden F, Jones D, Liang D, Gaskins AJ. Using follicular fluid metabolomics to investigate the association between air pollution and oocyte quality. Environ Int. 2022 Nov;169:107552. doi: 10.1016/j.envint.2022.107552. Epub 2022 Sep 28. PMID: 36191487; PMCID: PMC9620437.
Gaskins AJ, Tang Z, Hood RB, Ford J, Schwartz JD, Jones DP, Laden F, Liang D; EARTH Study Team. Periconception air pollution, metabolomic biomarkers, and fertility among women undergoing assisted reproduction. Environ Int. 2021 Oct;155:106666. doi: 10.1016/j.envint.2021.106666. Epub 2021 Jun 8. PMID: 34116378; PMCID: PMC8292230.